US delegation plane at Islamabad airport leaving Pakistan after failed negotiations with Iran
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Islamabad Talks Fail; JD Vance Leaves Pakistan Without Agreement with Tehran

US Vice President announces deadlock in 21-hour talks; Trump threatens blockade of the Strait of Hormuz.

edit_noterasastudy Editorialschedule4/12/2026menu_book4 min read

Intense and historic negotiations between the United States and Iran in Islamabad ended without result after 21 hours of non-stop consultations. JD Vance, announcing the failure of the talks, emphasized Washington's nuclear red lines and left Pakistan.

Diplomatic Marathon in Islamabad: 21 Hours Without Result Direct high-level negotiations between the delegations of the United States and the Islamic Republic of Iran, taking place in Islamabad, Pakistan, reached a deadlock after 21 hours of intense consultation [1.11]. JD Vance, the US Vice President, officially announced this morning (April 12, 2026) before boarding his private plane that the two sides were unable to reach an agreement to end the six-week conflict [1.5]. These talks, mediated by Pakistan at the Serena Hotel, were the first face-to-face meeting between high-ranking officials of the two countries in more than a decade [1.13].

The Core of the Disagreements; Nuclear Program and Long-term Guarantees According to JD Vance, the main obstacle to reaching an agreement was the Iranian delegation's refusal to accept definitive and long-term commitments to halt its nuclear program [1.7]. Vance stated in a brief press conference: "We need a proven commitment that Iran will not seek nuclear weapons or the means to rapidly acquire them. This is President Trump's main goal, which was not achieved in these negotiations" [1.12]. He also emphasized that although the talks were substantive, Tehran's lack of flexibility regarding Washington's red lines made continuing negotiations useless at this stage [1.9].

Tehran's Reaction: Mistrust and Criticism of US "Excessive Demands" In contrast, Mohammad Bagher Ghalibaf, the Speaker of the Iranian Parliament who headed the Iranian delegation, held Washington responsible for the failure of the negotiations. He announced in a message that Iran entered the field with "good faith and constructive initiatives," but the American side failed to gain the trust of the Iranian delegation [1.13]. Abbas Araghchi, the Iranian Foreign Minister who was part of the team, described the United States' conditions as "excessive" and added that Tehran would not ignore its nuclear rights and sovereignty over the Strait of Hormuz under pressure and threats [1.7]. Reports indicate that the Iranian economic team, led by Abdolnaser Hemmati, also failed to reach a final agreement regarding the release of frozen assets [1.15].

Consequences of the Failed Negotiations; Threat of Strait of Hormuz Blockade Immediately after the failure of the negotiations was announced, US President Donald Trump stated in a sharp reaction that the United States would "immediately" begin a blockade of ships in the Strait of Hormuz [1.12]. This comes as the US negotiating team, including Jared Kushner and Steve Witkoff, along with JD Vance, have left Pakistan [1.10]. With the departure of the negotiating teams, the fate of the 14-day temporary ceasefire previously agreed upon is shrouded in uncertainty. Pakistani officials, including Foreign Minister Ishaq Dar, have called on both sides to refrain from returning to violence, but the regional atmosphere is reported to be highly inflamed [1.5].

US VP JD Vance left Islamabad for Washington after 21 hours of inconclusive negotiations with Iranian officials.

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  1. JD Vance says talks failed due to Iran's refusal to give up nuclear programmeThe Guardian (2026-04-12)
  2. Trump says U.S. will blockade ships in Strait of Hormuz after no deal reachedCBS News (2026-04-12)
  3. US-Iran talks in Pakistan end after 21 hours with no dealTimes of Israel (2026-04-12)
  4. جی‌دی ونس: جمهوری اسلامی پس از ۲۱ ساعت مذاکره در پاکستان شروط صلح آمریکا را نپذیرفتPersian Epoch Times (2026-04-12)
  5. Vance says talks with Iran ended after 21 hours without reaching agreementLA Times (2026-04-11)
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